Our Real Betis vs Lyon Prediction: 1-2
Real Betis vs Lyon in the UEFA Europa League is scheduled for an 20:00 GMT kick-off on Thursday November 6, 2025. We anticipate a 1-2 away victory, but given both teams’ ability to score, BTTS seems like a valuable betting option.
This Real Betis vs Lyon prediction is backed by a deep dive into both teams' recent performances, key stats and head-to-head history — all of which you'll find detailed below to help you make an informed betting decision.
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Recent Form Insights
Real Betis's Last Match – Real Betis vs Mallorca
Real Betis will hope to extend their good run following a 3-0 Spain La Liga win against Mallorca on November 2. In that match, Real Betis saw 52% of the ball and created 13 goal attempts, with 8 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Real Betis | 52% | 13 (8) | 2.7 | 42 |
 Mallorca | 48% | 10 (1) | 0.62 | 58 |
Lyon's Last Match – Brest vs Lyon
Lyon must win as they look to rediscover their winning form following a 0-0 France Ligue 1 draw against Brest on November 2. In that match, Lyon had 50% possession and 2 attempts at goal, with 2 on target.
| Team | Possession | Shots (on target) | xG | Dangerous Attacks |
|---|---|---|---|---|
 Brest | 50% | 10 (4) | 1.34 | 66 |
 Lyon | 50% | 2 (2) | 0.18 | 31 |
Real Betis vs Lyon Stats
Key Stats
| Real Betis | Lyon | |
|---|---|---|
| 1.04 | Attacking Strength | 1.88 |
| 1.06 | Defence Strength | 0.69 |
| 2.1 | Points Per Game | 2 |
| 6/10 | WIN | 6/10 |
| 3/10 | DRAW | 2/10 |
| 4/10 | Clean Sheets | 6/10 |
| 5/10 | BTTS | 4/10 |
| 6/10 | Over 2.5 Goals | 4/10 |
| 2.3 | Average Scored | 1.5 |
Goals Scored vs Goals Conceded
Real Betis are averaging 2.3 goals scored and 0.9 conceded per match, while Lyon average 1.5 scored and 0.9 conceded per game.
Real Betis 23-9
Lyon 15-9
What are the odds for this match?
Real Betis to win: @1.85
Draw: @3.7
Lyon to win: @3.9
Over 2.5 Goals: @2.025
Lineups
Real Betis (4-3-3) : Alvaro Valles, Aitor Ruibal, Diego Llorente, Natan, Diego Gomez, Pablo Fornals, Giovani Lo Celso, Marc Roca, Antony, Cedric Bakambu, Abde Ezzalzouli
Lyon (4-3-3) : Dominik Greif, Ainsley Maitland-Niles, Ruben Kluivert, Moussa Niakhate, Abner Vinicius, Tanner Tessmann, Mathys De Carvalho, Khalis Merah, Adam Karabec, Martin Satriano, Enzo Anthony Honore Molebe